Impaired T-cell survival promotes mucosal inflammatory disease in SHIP1-deficient mice
نویسندگان
چکیده
منابع مشابه
gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses
Mucosal tissues of mice are enriched in T cells that express the gamma/delta T cell receptor. Since the function of these cells remains unclear, we have compared mucosal immune responses in gamma/delta T cell receptor-deficient (TCRdelta-/-) mice versus control mice of the same genetic background. The frequency of intestinal immunoglobulin (Ig) A plasma cells as well as IgA levels in serum, bil...
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ژورنال
عنوان ژورنال: Mucosal Immunology
سال: 2014
ISSN: 1933-0219,1935-3456
DOI: 10.1038/mi.2014.32